While all three KT frameworks presented here are useful and robust, KTA is a widely used model with which the Canadian Dementia Knowledge Translation Network (CDKTN) has worked previously. As the knowledge creation cycle is primarily complete (with the CCCDTD4 recommendations) the focus would be the on the action cycle. In identifying selleck Z-VAD-FMK the problem, consideration should be given to the fact that dementia is perceived by physicians as a difficult and time-consuming condition to treat and diagnose [1] and evidence-based clinical practice recommendations are often underused [8]. Thus it is crucial that the most current evidence-based clinical practice recommendations are effectively translated to assist physicians in providing the best care possible for patients with dementia.

Adapting the recommendations to the local context and intended target audience (that is, primary care physicians and their teams) and understanding potential barriers to uptake of these new recommendations can be greatly assisted through the inclusion of various stake-holder groups in the planning and execution process. Along with an examination of the current literature around dissemination to the intended target audience, there are a variety of options that (dependent on the planning structure for the project) include the following: inviting knowledge user groups/individuals to participate in a project committee or other project activities; surveying primary care health providers about their preferences for receiving such information; and participating in events or activities aimed at the target audience of primary care with the goal of engaging them in discussions around preferred methods of dissemination for such information.

In considering the development and execution of the KT plan, we would recommend an approach that targets GSK-3 not only the physicians, but also their healthcare teams. For that reason we would initially suggest the following be considered: 1. An online learning module (for example, CME) for the new recommendations that is aimed at a primary care audience – content for this can be derived from the CCCDTD4 and modified by the CDKTN. 2. The CDKTN’s knowledge exchange arm (Canadian Dementia Resource and Knowledge Exchange (CDRAKE)) can provide up to three webinars based on the recommendations, aimed at a broader audience that includes a variety of nonphysician healthcare professions.

3. Slide decks based on the new (and previous) Canadian Consensus Conference on the Diagnosis and Treatment of Dementia recommendations aimed at all treating physicians will be made available for download and use via the CDKTN’s website. 4. Other existing resources aimed at assisting primary care physicians with diagnosis and treatment of dementia selleck chem can be considered for inclusion of the new recommendations.