Procedure: sitting with bowls on wingspan distance, move marbles horizontally at table height from right to left with right arm as fast as possible and vice versa. Time needed to move 30 marbles is scored (seconds). Preceding the FCE tests subjects’ age and sex were PSI-7977 solubility dmso registered. Length and weight measurements were performed to calculate Body Mass Index (BMI). Tests were administered by 4th year physical therapy students who had received one-day training in the procedures and the execution of the FCE. They were trained and supervised by the research team. Statistical analysis Reference data were
matched for age and controlled for sex. For FCE results, two age categories were distinguished to allow analysis of the influence of ageing. Because of the small number of male subjects, the data were also compared for the whole group, to increase the statistical power. To answer study questions 1 Sapanisertib chemical structure and 2, SF-36 scores and FCE results of subjects with early OA and of the healthy workers were compared using t-tests. Mean differences and 95% confidence intervals between the groups were analysed.
Use of the 5th percentile as reference for job demands The rationale behind the study question about job demands is that the reference data were established to assist clinicians in assessing the functional capacity of a patient. By comparison with the reference values, a patient’s capacity can be classified into a physical demand category (sedentary—light—medium—heavy—very heavy) according to the Dictionary of Occupational Titles (DOT, U.S. Department of Labor 1991). It was assumed that the functional capacity of healthy workers was GDC 0032 clinical trial at least equal to their workload, because they worked 20 h or more per week, with no absenteeism due to musculoskeletal complaints during 1 year before the FCE. Therefore, this capacity
may be considered the ‘norm’ to which the functional capacity of patients can be compared. We chose to compare the results of the subjects with OA to the 5th percentile scores of the reference data on the lowest category, DOT-1 (‘sedentary work’, with Bumetanide occasionally lifting up to 4.5 kg): if the relatively weakest of the healthy workers can still meet their job demands, their functional capacity may be used as reference point. Results Subjects Subject characteristics and self-reported health status are presented in Table 1. Compared to healthy workers, subjects with early OA were older and less than half of them had a paid job. Women with early OA had a statistically significantly higher BMI than the female healthy workers. Table 1 Subject characteristics Males Females Variable Early OA Healthy Mean difference (95% CI) Early OA Healthy Mean difference (95% CI) n 15 183 78 92 Paid job (%) 47 100 47 100 Age in years: Mean (SD) 58 (5.3) 52 (4.1) −6 (−8.2– − 3.8)* 56 (4.8) 52 (4.0) −4 (−5.3– − 2.7)* Range 48–65 46–61 48–66 46–59 Body mass index# 25.8 (5.3) 25.6 (3.9) −0.2 (−1.9–2.3) 26.2 (4.