FLS closes the disparity between current knowledge and current practice. An important component of the Capture the Fracture Campaign will be to establish global reference standards for FLS. Several systematic reviews have highlighted that a range of service models have been designed to close the secondary fracture prevention care gap, with Transmembrane Transporters activator varying degrees

of success [72, 99, 100]. Having clarity on precisely what constitutes best practice will provide a mechanism for FLS in different localities and countries to learn from one buy Palbociclib another. The Capture the Fracture ‘Best Practice Framework’ described later in this position paper aims to provide a mechanism to facilitate this goal. How Capture the Fracture works Background The Capture the Fracture Campaign was launched at the IOF European Congress on Osteoporosis and Osteoarthritis in Bordeaux, France in March 2012. Healthcare Selleckchem RG-7388 professionals that have played a leading role in establishing FLS and representatives from national patient societies shared their efforts to embed FLS in national policy in their countries. In October 2012, the IOF World Osteoporosis Day report was devoted to Capture the Fracture [1] and disseminated at events organised by national societies throughout the world [101]. This position paper presents the aims and structure of the Capture the Fracture Campaign. A Steering

Committee comprised of the authorship group of this position paper has led development of the campaign and will provide ongoing support to the implementation of the next steps. Aims The aims of Capture the Fracture are: Standards: To provide internationally endorsed standards for best practice in secondary fracture prevention. Specific components are: Best Practice Framework Best Practice Recognition

Showcase of best practices Change: Facilitation of change at the local and national level will be achieved by: Mentoring programmes Implementation guides and toolkits Grant programme for developing systems Awareness: Knowledge of the challenges and opportunities presented by secondary fracture prevention will be raised globally by: An ongoing communications plan Anthology of literature, worldwide surveys and audits International coalition of partners Cobimetinib concentration and endorsers Internationally endorsed standards The centrepiece of the Capture the Fracture Campaign is the Best Practice Framework (BPF), provided as Appendix. The BPF is comprised of 13 standards which set an international benchmark for Fracture Liaison Services. Each standard has three levels of achievement: Level 1, Level 2 or Level 3. The BPF: 1. Defines the essential and aspirational building blocks that are necessary to implement a successful FLS, and   2. Serves as the measurement tool for IOF to award ‘Capture the Fracture Best Practice Recognition’ in celebration of successful FLS worldwide   Establishing standards for health care delivery systems that have global relevance is very difficult.