5-month follow-up confirmed Selleckchem BI-D1870 a benign outcome. Sensitivity, specificity, negative and positive predictive values and accuracy of FDG-PET/CT to differentiate lung cancer from benign disease were 97.7, 60.2, 92.5, 84.0 and 85.8%, respectively.
Lung cancer patients had a median referral, diagnostic and therapeutic delay of 7, 2 and 19 days, respectively. Conclusions: FDG-PET/CT in an RODP setting for suspected lung cancer has high performance in detecting cancer and facilitates timely care. Copyright (C) 2013 S. Karger AG, Basel”
“Introduction: Schwannomas are usually benign nerve sheath tumors, which typically arise in the head, neck, spinal cord and extremities. Schwannoma of the biliary tract is an extremely rare finding. Patients generally lack symptoms and seek medical attention when tumor growth causes obstructive jaundice. Preoperative diagnosis
is difficult and resection is the treatment of choice.
Methods: A 54 year-old female with history of back and right labia minor melanoma for which she underwent complete excision and right inguinal lymph node dissection more than 10 years ago, was evaluated for new onset gastroesophageal reflux symptoms and found to have markedly abnormal liver enzymes. Imagining studies revealed intrahepatic ductal dilatation and a 5.2 cm mass in the porta hepatis that was not consistent with cholangiocarcinoma or hepatocellular carcinoma. Multiple percutaneous biopsies of the mass failed to provide a definitive diagnosis. With a high clinical suspicion of metastatic melanoma and no other evident sites of disease, operative intervention was undertaken for diagnosis THZ1 datasheet and definitive treatment.
Results: Diagnostic laparoscopy
was performed initially, but access to the mass was difficult, given its location. Subsequently, the patient underwent laparotomy, with tumor BAY 63-2521 excision, common bile duct resection and hepato-jejunostomy. Pathologic examination and analysis were consistent with cellular schwannoma. Postoperatively, the patient recovered uneventfully, and liver function studies returned to normal.
Conclusion: Schwannomas are uncommon tumors, which very rarely arise from the biliary tract and cause biliary obstruction. Exploration is indicated in order to establish the diagnosis and to render definitive treatment. (C) 2011 Elsevier Ltd. All rights reserved.”
“To study the phase stability and the phase transformation behavior in the nanocrystalline (NC) stoichiometric alloys, a thermodynamic model has been developed in the present paper. Using the NC Sm-Co alloy as an example, the thermodynamic properties of various phases in the alloy system were evaluated systematically. In particular, the grain-size-dependence of the Gibbs free energy of each alloy phase at different temperatures was provided. Based on the model calculations, the stabilities of different phases in the NC Sm-Co system were analyzed.